Mechanical Design Engineer

Salary & Details: Competitive salary based on experience. Full Time

Benefits: Share Options; Flexible Holiday policy; On-site gym

Location: Stevenage

Report to: VP of Product Development

About MFX

MFX is an award-winning startup developing a break-through bioprocessing platform for the cell and gene therapy (CGT) market, based on microfluidic technology. Its platform allows ultra-low costs and scale-up of CGT from discovery to commercial stages, making these very potent treatments affordable for a wider number of patients, and reducing development times by several years. MicrofluidX is currently developing a system that will allow biologists to test dozens of cell culture conditions in parallel in an automated way replacing the Petri dish, the flask, the bag, the bioreactor, and the centrifuge all at once!

CGTs are fast-growing areas of medical development. With over 700 clinical trials in progress, some treatments (e.g. Kymriah, Yescarta) have already reached the market. This technology is at a critical juncture where advances are achieving clinical realisation, yet manufacturing remains a key challenge, hindering clinical development and patient accessibility. Three critical manufacturing hurdles remain: prohibitive costs of goods, low process stability and control, and lengthy scale-up from discovery to commercial stages.

Position Overview

It is an exciting time at MFX Bio as we develop a revolutionary system for the cell and gene therapy market. We are looking to recruit a Mechanical Design Engineer to help us develop this transformative technology. This is a broad role and will involve design activities ranging from consumable design to the mechanical and product design of our hardware.

Our platform will enable ultra-low-cost and scalable CGT production, expediting the journey from discovery to commercialization with unprecedented efficiency. Joining MFX presents a unique opportunity to shape the future of bioprocessing technologies, contributing to the vision of making advanced therapies more accessible and cost-effective for a broader patient base while significantly reducing development timelines.

The Mechanical Design Engineer role will span both the design of prototypes, rigs and also the production design of our products and will ensure best design practices to meet medical device and GMP standards where appropriate.

Responsibilities and duties

• Help create technical and user requirements of the products
• Develop designs of prototypes and our products in 3D CAD
• Analyse and simulate designs using finite element analysis (FEA) and tools such as tolerance analysis
• Create 2D drawings of designs to share with manufacturing partners
• Participate in design reviews and design for manufacture assessments
• Help create quality documentation in support of designs such as dFMEAs
• Project manage suppliers to manufacture parts
• Build and test prototypes and rigs and iterate the design as required

Qualifications and Experience:

• A degree in a mechanical engineering (first or 2:1)
• 3+ years of experience of 3D CAD modelling preferably using SolidWorks
• 3+ years of experience designing high volume medical consumables
• 3+ years of experience of part design for injection moulding
• 3+ years of experience of creating engineering part and assembly drawings in CAD and applying GD&T
• Experience of mechanical design of rigs and prototypes
• Experience of design for manufacture
• Experience of analysing design using simulation software such as FEA
• Experience of tolerance analysis
• Experience in the project managing manufacturing partners