MFX's summer of studentsWhy investing time in the next generation helps give us new insights into our own technologies. A common theme that has come up within the team at MFX is that when we were making decisions earlier on in our careers, the information about what...

From cell culture to cell therapy - the biggest challenges of growing cells ex vivoDuring the development of the Cyto Engine platform we interviewed over 100 experts in cell culture and cell therapy manufacturing to understand what their biggest challenges were when...

Cutting the cost of CAR-Ts – Innovative strategies to make cell therapies more affordableT cells are the most extensively studied cell type in the development of cell therapies, constituting 58% of active UK ATMP clinical trials (1). CAR-T (Chimeric Antigen Receptor T...

Embracing Inclusivity: The CGT Circle X Pride - A Recap of The CGT Circle’s First-Ever WorkshopLast month The CGT Circle held it's first ever workshop event at Stevenage Bioscience Catalyst (SBC), supported by MFX and SBC and facilitated by The Honeycomb Works. A...

How to Innovate? The MFX wayCésaré Cejas, PhD gave a recent talk at the Bioengineering Symposium, a jointly organised event held by the Oxford University Bioengineering Society and Warwick BioSoc on the topic of "conceptualising innovations to confront current...

The Best Cell and Gene Therapy Conferences in 2024What are the best Cell and Gene Therapy conferences to attend in 2024?  We asked our VP of Commercial Lindsey Clarke what her top picks are for the coming year. It really depends on what your reasons are for wanting to...

Data and Digitization – The key to better biology and more effective therapiesData is the cornerstone of any scientific endeavor. But throughout history it’s been managed pretty poorly. Most data ever gathered on cells remain in hand-written lab notebooks, gathering...

Making cell therapies comPATible with large scale manufacturingProcess analytical technologies (PATs) cover a wide range of tools, playing an important role in initiatives such as quality by design (QbD), real-time release, and continuous manufacturing [1]. They are...

How do you solve a problem like scaling up microfluidics?Culturing cells using microfluidics offers several advantages over traditional cell culture techniques – the main one being the ability to precisely control the microenvironment. This means the availability of...

Make your cells feel at home with microfluidicsIt can be easy to forget just how alien an environment in vitro culture is when culturing cells. In vivo, cells exist in a multi-faceted micro-environment made up of a carefully regulated biochemical milieu combined with...

Microfluidics- the perfect meeting-place for viruses and cellsViruses get a bad press. SARS-CoV-2 did little to improve matters, but those of us working in gene and cell therapy are only too aware of the critical role lentiviruses, adeno- and adeno-associated viruses...

Scale up, look sharp – why analytics in large-scale cell therapy manufacture is so difficultCAR-T and other cell and gene therapies represent an exciting new paradigm in how we approach previously untreatable diseases. But as ‘living drugs’ where the cell is the...